An Evaluation of Fine Needle Aspiration Cytology (FNAC) for Diagnostic Purposes
Abstract
This study focuses on breast lesions, a significant contributor to illness and death among women. Early diagnosis and treatment are crucial to prevent severe complications. Fine Needle Aspiration Cytology (FNAC) serves as an effective diagnostic method with a high degree of accuracy. The primary aim of this study was to assess the reliability of FNAC in diagnosing palpable breast lumps. Additionally, it aimed to establish a correlation between cytological findings and histopathological analysis of surgically removed tissue samples. A retrospective study approach was adopted, involving FNAC procedures conducted on 180 patients, with 105 cases forming the core study group. The findings revealed that the average age of these 105 patients was 32 years. Among them, 54 had lumps in the left breast, 45 in the right breast, and 4 had bilateral lumps. Cytological examination identified 77 cases as benign, 34 as malignant, and 5 as atypical or suspicious. Histopathological analysis confirmed 77 benign cases, 26 malignant cases, and 1 atypical/suspicious case. The cyto-histological agreement was found to be 93.05% for fibroadenoma and 79.2% for infiltrating ductal carcinoma. The FNAC procedure demonstrated an overall sensitivity of 94.17%, specificity of 100%, and accuracy of 93.26%. Based on these findings, FNAC is confirmed to be a simple yet highly reliable technique for diagnosing both benign and malignant breast lesions, making it an essential tool in breast lump evaluation.
Keywords: Cytology, Fine Needle, Women, Cancer.
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